E-106 is a robot created by Doctor Eggman.
- E-106’s title implies that it is a part of the E-100 series first seen in Sonic Adventure, but this has yet to be confirmed.
- E-106 physically resembles ZERO, another robot that originated from Sonic Adventure.
- In the Archie Comics continuity, a different robot with the E-106 designation appeared. This version, codenamed “Eta”, had a completely different appearance, appearing closer in design to its five E-100 series predecessors.